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Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib

The proteasome inhibitor and anti-cancer drug bortezomib was tested for in vitro activity against bloodstream forms of Trypanosoma brucei. The concentrations of bortezomib required to reduce the growth rate by 50% and to kill all trypanosomes were 3.3 nM and 10 nM, respectively. In addition, bortezo...

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Detaylı Bibliyografya
Asıl Yazarlar: Steverding, Dietmar, Wang, Xia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714034/
https://ncbi.nlm.nih.gov/pubmed/19583840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-2-29
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