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Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib
The proteasome inhibitor and anti-cancer drug bortezomib was tested for in vitro activity against bloodstream forms of Trypanosoma brucei. The concentrations of bortezomib required to reduce the growth rate by 50% and to kill all trypanosomes were 3.3 nM and 10 nM, respectively. In addition, bortezo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714034/ https://ncbi.nlm.nih.gov/pubmed/19583840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-2-29 |
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