Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells

BACKGROUND: Src family kinases control multiple cancer cell properties including cell cycle progression, survival, and metastasis. Recent studies suggest that the Src inhibitor dasatinib blocks these critical cancer cell functions. METHODS: Because the molecular mechanism of action of dasatinib in b...

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Detalhes bibliográficos
Main Authors: Pichot, C S, Hartig, S M, Xia, L, Arvanitis, C, Monisvais, D, Lee, F Y, Frost, J A, Corey, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713704/
https://ncbi.nlm.nih.gov/pubmed/19513066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605101
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