Structural Basis for the Product Specificity of Histone Lysine Methyltransferases

DIM-5 is a SUV39-type histone H3 Lys9 methyltransferase that is essential for DNA methylation in N. crassa. We report the structure of a ternary complex including DIM-5, S-adenosyl-l-homocysteine, and a substrate H3 peptide. The histone tail inserts as a parallel strand between two DIM-5 strands, co...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhang, Xing, Yang, Zhe, Khan, Seema I., Horton, John R., Tamaru, Hisashi, Selker, Eric U., Cheng, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713655/
https://ncbi.nlm.nih.gov/pubmed/12887903
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge