OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER) α and Affects ERα Transcriptional Activity

Estrogen receptor (ER) α is an essential component in human physiology and is a key factor involved in the development of breast and endometrial cancers. ERα protein levels and transcriptional activity are tightly controlled by the ubiquitin proteasome system. Deubiquitinating enzymes, a class of pr...

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Detalhes bibliográficos
Main Authors: Stanišić, Vladimir, Malovannaya, Anna, Qin, Jun, Lonard, David M., O'Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713518/
https://ncbi.nlm.nih.gov/pubmed/19383985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007484
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