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Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer

BACKGROUND: Osteopontin (OPN) is a secreted phosphoprotein which functions as a cell attachment protein and cytokine that signals through two cell adhesion molecules, α(v)β(3)-integrin and CD44, to regulate cancer growth and metastasis. However, the signaling pathways associated with OPN have not be...

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Bibliografiska uppgifter
Huvudupphovsmän: Mi, Zhiyong, Guo, Hongtao, Kuo, Paul C
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713255/
https://ncbi.nlm.nih.gov/pubmed/19570203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-119
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