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Osteopontin Regulates Epithelial Mesenchymal Transition-Associated Growth of Hepatocellular Cancer in a Mouse Xenograft Model
OBJECTIVE: To determine the efficacy of osteopontin (OPN) targeting in hepatocellular cancer (HCC). SUMMARY/BACKGROUND: OPN is associated with HCC growth and metastasis and represents a unique therapeutic target. METHODS: OPN and EMT markers, α-smooth muscle actin (SMA), vimentin and tenascin-c, wer...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725267/ https://ncbi.nlm.nih.gov/pubmed/22241292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e31823e3a1c |
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