A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning

Previous studies suggest that selective antagonists of specific subtypes of muscarinic acetylcholine receptors (mAChRs) may provide a novel approach for the treatment of certain central nervous system (CNS) disorders, including epileptic disorders, Parkinson's disease, and dystonia. Unfortunate...

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Hauptverfasser: Sheffler, Douglas J., Williams, Richard, Bridges, Thomas M., Xiang, Zixiu, Kane, Alexander S., Byun, Nellie E., Jadhav, Satyawan, Mock, Mathew M., Zheng, Fang, Lewis, L. Michelle, Jones, Carrie K., Niswender, Colleen M., Weaver, Charles D., Lindsley, Craig W., Conn, P. Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713127/
https://ncbi.nlm.nih.gov/pubmed/19407080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.056531
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