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A single charged voltage sensor is capable of gating the Shaker K(+) channel

We sought to determine the contribution of an individual voltage sensor to Shaker's function. Concatenated heterotetramers of Shaker zH4 Δ(6–46) wild type (wt) in combination with a neutral S4 segment Shaker mutant (mut) with stoichiometries 2wt/2mut and 1wt/3mut were studied and compared with...

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Hlavní autoři: Gagnon, Dominique G., Bezanilla, Francisco
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712970/
https://ncbi.nlm.nih.gov/pubmed/19398775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810082
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