Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization

Sphingomyelin plays a very important role both in cell membrane formation that may well have an impact on the development of diseases like atherosclerosis and diabetes. However, the molecular mechanism that governs intracellular and plasma membrane SM levels is largely unknown. Recently, two isoform...

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Main Authors: Li, Zhiqiang, Hailemariam, Tiruneh K., Zhou, Hongwen, Li, Yan, Duckworth, Dale C., Peake, David A., Zhang, Youyan, Kuo, Ming-Shang, Cao, Guoqing, Jiang, Xian-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712822/
https://ncbi.nlm.nih.gov/pubmed/17616479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2007.05.007
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