Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization

Sphingomyelin plays a very important role both in cell membrane formation that may well have an impact on the development of diseases like atherosclerosis and diabetes. However, the molecular mechanism that governs intracellular and plasma membrane SM levels is largely unknown. Recently, two isoform...

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Autori principali: Li, Zhiqiang, Hailemariam, Tiruneh K., Zhou, Hongwen, Li, Yan, Duckworth, Dale C., Peake, David A., Zhang, Youyan, Kuo, Ming-Shang, Cao, Guoqing, Jiang, Xian-Cheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712822/
https://ncbi.nlm.nih.gov/pubmed/17616479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2007.05.007
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