Spongipyran Synthetic Studies. Total Synthesis of (+)-Spongistatin 2

Evolution of a convergent synthetic strategy to access (+)-spongistatin 2 (2), a potent cytotoxic marine macrolide, is described. Highlights of the synthesis include: development of a multicomponent dithiane-mediated linchpin union tactic, devised and implemented specifically for construction of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smith, Amos B., Lin, Qiyan, Doughty, Victoria A., Zhuang, Linghang, McBriar, Mark D., Kerns, Jeffrey K., Boldi, Armen M., Murase, Noriaki, Moser, William H., Brook, Christopher S., Bennett, Clay S., Nakayama, Kiyoshi, Sobukawa, Masao, Lee Trout, Robert E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712115/
https://ncbi.nlm.nih.gov/pubmed/20161196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.04.001
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