Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1

Sex hormones regulate cholangiocyte hyperplasia in bile duct-ligated (BDL) rats. We studied whether follicle-stimulating hormone (FSH) regulates cholangiocyte proliferation. FSH receptor (FSHR) and FSH expression was evaluated in liver sections, purified cholangiocytes, and cholangiocyte cultures (N...

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Autors principals: Mancinelli, Romina, Onori, Paolo, Gaudio, Eugenio, DeMorrow, Sharon, Franchitto, Antonio, Francis, Heather, Glaser, Shannon, Carpino, Guido, Venter, Julie, Alvaro, Domenico, Kopriva, Shelley, White, Mellanie, Kossie, Ashley, Savage, Jennifer, Alpini, Gianfranco
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Liver and Biliary Tract
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711748/
https://ncbi.nlm.nih.gov/pubmed/19389804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00025.2009
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