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Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes
BACKGROUND & AIMS: Secretin stimulates ductal secretion by interacting with secretin receptor (SR) activating cAMP⇒CFTR⇒Cl(−)/HCO(3)(−) AE2 signaling that is elevated by biliary hyperplasia. Cholangiocytes secrete several neuroendocrine factors regulating biliary functions by autocrine mechanism...
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566412/ https://ncbi.nlm.nih.gov/pubmed/23080076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26105 |
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