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Sepiapterin reductase regulation of endothelial tetrahydrobiopterin and nitric oxide bioavailability

Sepiapterin reductase (SPR) catalyzes the final step of tetrahydrobiopterin (H(4)B) biosynthesis and the first step of H(4)B regeneration from an exogenous precursor sepiapterin. Despite the potential significance of SPR in regulating H(4)B-dependent nitric oxide (NO(•)) production, the endothelium-...

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Bibliografski detalji
Glavni autori: Gao, Ling, Pung, Yuh-Fen, Zhang, Jun, Chen, Peng, Wang, Ting, Li, Min, Meza, Miguel, Toro, Ligia, Cai, Hua
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711718/
https://ncbi.nlm.nih.gov/pubmed/19429835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00007.2009
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