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Sepiapterin reductase regulation of endothelial tetrahydrobiopterin and nitric oxide bioavailability
Sepiapterin reductase (SPR) catalyzes the final step of tetrahydrobiopterin (H(4)B) biosynthesis and the first step of H(4)B regeneration from an exogenous precursor sepiapterin. Despite the potential significance of SPR in regulating H(4)B-dependent nitric oxide (NO(•)) production, the endothelium-...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711718/ https://ncbi.nlm.nih.gov/pubmed/19429835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00007.2009 |
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