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spFRET Using Alternating Excitation and FCS Reveals Progressive DNA Unwrapping in Nucleosomes
Accessibility to DNA wrapped in nucleosomes is essential for nuclear processes such as DNA transcription. Large conformational changes in nucleosome structure are required to facilitate protein binding to target sites within nucleosomal DNA. Transient unwrapping of DNA from nucleosome ends can provi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711358/ https://ncbi.nlm.nih.gov/pubmed/19580757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.030 |
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