spFRET Using Alternating Excitation and FCS Reveals Progressive DNA Unwrapping in Nucleosomes

Accessibility to DNA wrapped in nucleosomes is essential for nuclear processes such as DNA transcription. Large conformational changes in nucleosome structure are required to facilitate protein binding to target sites within nucleosomal DNA. Transient unwrapping of DNA from nucleosome ends can provi...

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Autori principali: Koopmans, W.J.A., Buning, R., Schmidt, T., van Noort, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2009
Soggetti:
Nucleic Acid
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711358/
https://ncbi.nlm.nih.gov/pubmed/19580757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.030
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