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Hidden Markov Analysis of Nucleosome Unwrapping Under Force
Transient conformational changes of DNA-protein complexes play an important role in the DNA metabolism but are generally difficult to resolve. Single molecule force spectroscopy has the unique capability to follow such reactions but Brownian fluctuations in the end-to-end distance of a DNA tether ca...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711431/ https://ncbi.nlm.nih.gov/pubmed/19413976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.048 |
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