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Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy
The proteasome and the autophagy systems are two evolutionarily conserved mechanisms for degrading intracellular materials. They are functionally coupled and suppression of the proteasome promotes autophagy. While suppression of the proteasome leads to cell death, suppression of autophagy can be eit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711219/ https://ncbi.nlm.nih.gov/pubmed/19584239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1169 |
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