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Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

Damaged mitochondria can be eliminated by autophagy, i.e. mitophagy, which is important for cellular homeostasis and cell survival. Despite the fact that a number of factors have been found to be important for mitophagy in mammalian cells, their individual roles in the process had not been clearly d...

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Autores principales: Ding, Wen-Xing, Ni, Hong-Min, Li, Min, Liao, Yong, Chen, Xiaoyun, Stolz, Donna B., Dorn, Gerald W., Yin, Xiao-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934655/
https://ncbi.nlm.nih.gov/pubmed/20573959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.119537
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