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Role of Intracellular Calcium in Proteasome Inhibitor-induced Endoplasmic Reticulum Stress, Autophagy and Cell Death

PURPOSE: Proteasome inhibition induces endoplasmic reticulum (ER) stress and compensatory autophagy to relieve ER stress. Disturbance of intracellular calcium homeostasis can lead to ER stress and alter the autophagy process. It has been suggested that inhibition of the proteasome disrupts intracell...

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Bibliografski detalji
Glavni autori: Williams, Jessica A., Hou, Yifeng, Ni, Hong-Min, Ding, Wen-Xing
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788613/
https://ncbi.nlm.nih.gov/pubmed/23893020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1139-8
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