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Role of Intracellular Calcium in Proteasome Inhibitor-induced Endoplasmic Reticulum Stress, Autophagy and Cell Death
PURPOSE: Proteasome inhibition induces endoplasmic reticulum (ER) stress and compensatory autophagy to relieve ER stress. Disturbance of intracellular calcium homeostasis can lead to ER stress and alter the autophagy process. It has been suggested that inhibition of the proteasome disrupts intracell...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788613/ https://ncbi.nlm.nih.gov/pubmed/23893020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1139-8 |
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