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Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified mutations that contribute to myeloid transformation. Based on the recent identification of TET2 mutations, we evaluated the mutational status of TET1, TET2, and TET3 in my...

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Detalhes bibliográficos
Main Authors: Abdel-Wahab, Omar, Mullally, Ann, Hedvat, Cyrus, Garcia-Manero, Guillermo, Patel, Jay, Wadleigh, Martha, Malinge, Sebastien, Yao, JinJuan, Kilpivaara, Outi, Bhat, Rukhmi, Huberman, Kety, Thomas, Sabrena, Dolgalev, Igor, Heguy, Adriana, Paietta, Elisabeth, Le Beau, Michelle M., Beran, Miloslav, Tallman, Martin S., Ebert, Benjamin L., Kantarjian, Hagop M., Stone, Richard M., Gilliland, D. Gary, Crispino, John D., Levine, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710942/
https://ncbi.nlm.nih.gov/pubmed/19420352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210039
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