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Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways

APC/Cdh1 is a major cell cycle regulator and its function has been implicated in DNA damage repair; however, its exact role remains unclear. Using affinity purification coupled with mass spectrometry, we identified Claspin as a novel Cdh1-interacting protein and further demonstrated that Claspin is...

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Detalhes bibliográficos
Main Authors: Gao, Daming, Inuzuka, Hiroyuki, Korenjak, Michael, Tseng, Alan, Wu, Tao, Wan, Lixin, Kirschner, Marc, Dyson, Nicholas, Wei, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710831/
https://ncbi.nlm.nih.gov/pubmed/19477924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0092
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