mTOR regulates memory CD8 T cell differentiation

Memory CD8 T cells are a critical component of protective immunity and inducing effective memory T cell responses is a major goal of vaccines against chronic infections and tumors 1-3. Considerable effort has gone into designing vaccine regimens that will increase the magnitude of the memory respons...

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Bibliographic Details
Main Authors: Araki, Koichi, Turner, Alexandra P., Shaffer, Virginia Oliva, Gangappa, Shivaprakash, Keller, Susanne A., Bachmann, Martin F., Larsen, Christian P., Ahmed, Rafi
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710807/
https://ncbi.nlm.nih.gov/pubmed/19543266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08155
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