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The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data

The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor system in mammalian cells, and it also has become a popular example for employing mathematical modeling to cellular signaling networks. Dynamic models have the highest explanatory and predictive poten...

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Autores principales: Samaga, Regina, Saez-Rodriguez, Julio, Alexopoulos, Leonidas G., Sorger, Peter K., Klamt, Steffen
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710522/
https://ncbi.nlm.nih.gov/pubmed/19662154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000438
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