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A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer’s disease mouse model

Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs memory and cognition. One of the major neuropathological hallmarks is the accumulation of the extracellular senile plaques that are mainly composed of amyloid beta (Aβ) protein. Plaques are associated with synapse loss, dystrophic...

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Detalhes bibliográficos
Main Authors: Rozkalne, Anete, Spires-Jones, Tara L, Stern, Edward A, Hyman, Bradley T
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709805/
https://ncbi.nlm.nih.gov/pubmed/19465012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.05.045
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