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A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer’s disease mouse model

Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs memory and cognition. One of the major neuropathological hallmarks is the accumulation of the extracellular senile plaques that are mainly composed of amyloid beta (Aβ) protein. Plaques are associated with synapse loss, dystrophic...

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Hlavní autoři: Rozkalne, Anete, Spires-Jones, Tara L, Stern, Edward A, Hyman, Bradley T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709805/
https://ncbi.nlm.nih.gov/pubmed/19465012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.05.045
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