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CD8+ Th17 Mediate Costimulation Blockade Resistant Allograft Rejection in T-bet Deficient Mice
While studying T helper (Th) responses induced by cardiac transplantation, we observed that mice deficient in the Th1 transcription factor T-bet (T-bet-/-) mount both Th1 and Th17 responses, while wild type (WT) recipients mount only Th1 responses. Cells producing both IFNγ and IL-17 were readily de...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709752/ https://ncbi.nlm.nih.gov/pubmed/18768845 |
| Ετικέτες: |
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