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IL-6 Promotes Cardiac Graft Rejection Mediated by CD4+ Cells()

IL-6 mediates numerous immunologic effects relevant to transplant rejection; however its specific contributions to these processes are not fully understood. To this end, we neutralized IL-6 in settings of acute cardiac allograft rejection associated with either CD8+ or CD4+ cell dominant responses....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Booth, Adam Jared, Grabauskiene, Svetlana, Wood, Sherri Chan, Lu, Guanyi, Burrell, Bryna E., Bishop, D. Keith
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221839/
https://ncbi.nlm.nih.gov/pubmed/22025555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100766
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