Nck Proteins Maintain the Adult Glomerular Filtration Barrier

Within the glomerulus, the scaffolding protein nephrin bridges the actin-rich foot processes that extend from adjacent podocytes to form the slit diaphragm. Mutations affecting a number of slit diaphragm proteins, including nephrin, cause glomerular disease through rearrangement of the actin cytoske...

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Autors principals: Jones, Nina, New, Laura A., Fortino, Megan A., Eremina, Vera, Ruston, Julie, Blasutig, Ivan M., Aoudjit, Lamine, Zou, Youling, Liu, Xiuwen, Yu, Guo-Liang, Takano, Tomoko, Quaggin, Susan E., Pawson, Tony
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2009
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709686/
https://ncbi.nlm.nih.gov/pubmed/19443634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010056
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