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Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol

DNA methylation is a key regulator of gene transcription. Alterations in DNA methylation patterns are common in most cancers, occur early in carcinogenesis and can be detected in body fluids. Reliable and sensitive quantitative assays are required to improve the diagnostic role of methylation in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Malentacchi, Francesca, Forni, Giulia, Vinci, Serena, Orlando, Claudio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709587/
https://ncbi.nlm.nih.gov/pubmed/19454604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp383
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