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Quantitation of DNA methylation by melt curve analysis
BACKGROUND: Methylation of DNA is a common mechanism for silencing genes, and aberrant methylation is increasingly being implicated in many diseases such as cancer. There is a need for robust, inexpensive methods to quantitate methylation across a region containing a number of CpGs. We describe and...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679043/ https://ncbi.nlm.nih.gov/pubmed/19393074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-123 |
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