Quantitative evaluation of DNMT3B promoter methylation in breast cancer patients using differential high resolution melting analysis

DNA methylation plays an important role in carcinogenesis through epigenetic silencing of tumor suppressor genes. Aberrant methylation usually results from changes in the activity of DNA methyltransferases (DNMTs). Some studies show that the overexpression of the DNMTs may lead to aberrant methylati...

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Main Authors: Naghitorabi, M., Mohammadi Asl, J., Mir Mohammad Sadeghi, H., Rabbani, M., Jafarian-Dehkordi, A., Javanmard, Haghjooye S.
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764668/
https://ncbi.nlm.nih.gov/pubmed/24019826
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