Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes

DNA oligonucleotides (ODN) applied to an organism are known to modulate the innate and adaptive immune system. Previous studies showed that a CpG-containing ODN (CpG-1-PTO) and interestingly, also a non-CpG-containing ODN (nCpG-5-PTO) suppress inflammatory markers in skin. In the present study it wa...

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Main Authors: Kippenberger, Stefan, Müller, Jutta, Schultz, Maike, Dorn, Annette, Bock, Andreas, Aygün, Hüseyin, Thaçi, Diamant, Hofmann, Matthias, Kaufmann, Roland, Bernd, August
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709556/
https://ncbi.nlm.nih.gov/pubmed/19386618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp252
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