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Lowering of Tumor Interstitial Fluid Pressure Reduces Tumor Cell Proliferation in a Xenograft Tumor Model

High tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. TIFP may hamper adequate uptake of macromolecular therapeutics in tumor tissue. In addition, TIFP generates mechanical forces affecting the tumor cortex, which might influence the growth parameters of tumor cells...

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Detalhes bibliográficos
Main Authors: Hofmann, Matthias, Guschel, Maike, Bernd, August, Bereiter-Hahn, Jürgen, Kaufmann, Roland, Tandi, Christa, Wiig, Helge, Kippenberger, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578509/
https://ncbi.nlm.nih.gov/pubmed/16611401
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