Increased Plasma Colloid Osmotic Pressure Facilitates the Uptake of Therapeutic Macromolecules in a Xenograft Tumor Model

Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy. In this study, a means of modulating TIFP to increase the flux of macromolecules int...

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Main Authors: Hofmann, Matthias, McCormack, Emmet, Mujiç, Maja, Roßberg, Maila, Bernd, August, Bereiter-Hahn, Jürgen, Gjertsen, Bjørn Tore, Wiig, Helge, Kippenberger, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713396/
https://ncbi.nlm.nih.gov/pubmed/19649211
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