Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes

DNA oligonucleotides (ODN) applied to an organism are known to modulate the innate and adaptive immune system. Previous studies showed that a CpG-containing ODN (CpG-1-PTO) and interestingly, also a non-CpG-containing ODN (nCpG-5-PTO) suppress inflammatory markers in skin. In the present study it wa...

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Bibliografiske detaljer
Main Authors: Kippenberger, Stefan, Müller, Jutta, Schultz, Maike, Dorn, Annette, Bock, Andreas, Aygün, Hüseyin, Thaçi, Diamant, Hofmann, Matthias, Kaufmann, Roland, Bernd, August
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709556/
https://ncbi.nlm.nih.gov/pubmed/19386618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp252
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