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Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes

DNA oligonucleotides (ODN) applied to an organism are known to modulate the innate and adaptive immune system. Previous studies showed that a CpG-containing ODN (CpG-1-PTO) and interestingly, also a non-CpG-containing ODN (nCpG-5-PTO) suppress inflammatory markers in skin. In the present study it wa...

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Detalhes bibliográficos
Main Authors: Kippenberger, Stefan, Müller, Jutta, Schultz, Maike, Dorn, Annette, Bock, Andreas, Aygün, Hüseyin, Thaçi, Diamant, Hofmann, Matthias, Kaufmann, Roland, Bernd, August
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709556/
https://ncbi.nlm.nih.gov/pubmed/19386618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp252
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