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Non-catalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of PPARγ

The naturally occurring nitroalkenes, nitrolinoleic (NO(2)-LA) and nitrooleic (NO(2)-OA) acids, are among the most potent endogenous ligand activators of PPARγ-dependent transcription. In order to understand mechanisms that regulate cellular response to these nitroalkenes, we previously demonstrated...

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Autors principals: Bates, Darcy J. P., Lively, Mark O., Gorczynski, Michael J., King, S. Bruce, Townsend, Alan J., Morrow, Charles S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709414/
https://ncbi.nlm.nih.gov/pubmed/19358561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900224c
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