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Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPARγ-dependent transcription by distinct signaling pathways and with significantly different potencies()

Naturally occurring nitroalkene fatty acids (NAs) derived from oleic (NO(2)-OA) and linoleic (NO(2)-LA) acids mediate a variety of cellular responses. We examined the signaling pathways involved in NA activation of Nrf2/ARE-dependent versus PPARγ/PPRE-dependent transcription in human MCF7 breast can...

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Detalhes bibliográficos
Main Authors: Bates, Darcy J. P., Smitherman, Pamela K., Townsend, Alan J., King, S. Bruce, Morrow, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168690/
https://ncbi.nlm.nih.gov/pubmed/21827153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2005784
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