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Rrs1 Is Involved in Endoplasmic Reticulum Stress Response in Huntington Disease
The induction of Rrs1 expression is one of the earliest events detected in a presymptomatic knock-in mouse model of Huntington disease (HD). Rrs1 up-regulation fulfills the HD criteria of dominance, striatal specificity, and polyglutamine dependence. Here we show that mammalian Rrs1 is localized bot...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709382/ https://ncbi.nlm.nih.gov/pubmed/19433866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018325 |
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