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Queuosine Formation in Eukaryotic tRNA Occurs via a Mitochondria-localized Heteromeric Transglycosylase

tRNA guanine transglycosylase (TGT) enzymes are responsible for the formation of queuosine in the anticodon loop (position 34) of tRNA(Asp), tRNA(Asn), tRNA(His), and tRNA(Tyr); an almost universal event in eubacterial and eukaryotic species. Despite extensive characterization of the eubacterial TGT...

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Detalhes bibliográficos
Main Authors: Boland, Coilin, Hayes, Patti, Santa-Maria, Ismael, Nishimura, Susumu, Kelly, Vincent P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709355/
https://ncbi.nlm.nih.gov/pubmed/19414587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002477
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