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Thiolation Controls Cytoplasmic tRNA Stability and Acts as a Negative Determinant for tRNA Editing in Mitochondria

Kinetoplastids encode a single nuclear tryptophanyl tRNA that contains a CCA anticodon able to decode the UGG codons used in cytoplasmic protein synthesis but cannot decode the mitochondrial UGA codons. Following mitochondrial import, this problem is circumvented in Trypanosoma brucei by specificall...

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Détails bibliographiques
Auteurs principaux: Wohlgamuth-Benedum, Jessica M., Rubio, Mary Anne T., Paris, Zdeněk, Long, Shaojun, Poliak, Pavel, Lukeš, Julius, Alfonzo, Juan D.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781988/
https://ncbi.nlm.nih.gov/pubmed/19574216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029421
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