Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein kinase C) family kinases such as Akt (protein kinase B), S6K (p70 ribosomal S6 kinase) and SGK (serum and glucocorticoid protein kinase). mTORC1 (...

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Bibliografske podrobnosti
Main Authors: García-Martínez, Juan M., Moran, Jennifer, Clarke, Rosemary G., Gray, Alex, Cosulich, Sabina C., Chresta, Christine M., Alessi, Dario R.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708931/
https://ncbi.nlm.nih.gov/pubmed/19402821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090489
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