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Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein kinase C) family kinases such as Akt (protein kinase B), S6K (p70 ribosomal S6 kinase) and SGK (serum and glucocorticoid protein kinase). mTORC1 (...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708931/ https://ncbi.nlm.nih.gov/pubmed/19402821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090489 |
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