RasGRP1 Transgenic Mice Develop Cutaneous Squamous Cell Carcinomas in Response to Skin Wounding : Potential Role of Granulocyte Colony-Stimulating Factor

Models of epidermal carcinogenesis have demonstrated that Ras is a critical molecule involved in tumor initiation and progression. Previously, we have shown that RasGRP1 increases the susceptibility of mice to skin tumorigenesis when overexpressed in the epidermis by a transgenic approach, related t...

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Autors principals: Diez, Federico R., Garrido, Ann A., Sharma, Amrish, Luke, Courtney T., Stone, James C., Dower, Nancy A., Cline, J. Mark, Lorenzo, Patricia S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708824/
https://ncbi.nlm.nih.gov/pubmed/19497993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090036
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