Targeted deletion of RasGRP1 impairs skin tumorigenesis

Ras is frequently activated in cutaneous squamous cell carcinoma, a prevalent form of skin cancer. However, the pathways that contribute to Ras-induced transformation have not been entirely elucidated. We have previously demonstrated that in transgenic mice, overexpression of the Ras activator RasGR...

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Detalhes bibliográficos
Main Authors: Sharma, Amrish, Fonseca, Lauren L., Rajani, Cynthia, Yanagida, Jodi K., Endo, Yuka, Cline, J.Mark, Stone, James C., Ji, Junfang, Ramos, Joe W., Lorenzo, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004207/
https://ncbi.nlm.nih.gov/pubmed/24464785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu016
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