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The Urokinase Receptor Promotes Cancer Metastasis Independently of Urokinase-Type Plasminogen Activator in Mice

The urokinase receptor (uPAR) promotes metastasis of human malignancies; however, its mechanism of action remains incompletely understood. Established models focus on the ability of uPAR to bind urokinase-type plasminogen activator (uPA) and promote protease activation in the tumor cell microenviron...

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Detalhes bibliográficos
Main Authors: Jo, Minji, Takimoto, Shinako, Montel, Valerie, Gonias, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708805/
https://ncbi.nlm.nih.gov/pubmed/19497996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081053
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