Decrease in Tumor Necrosis Factor-α Receptor-Associated Death Domain Results from Ubiquitin-Dependent Degradation in Obstructive Renal Injury in Rats

Increased expression levels of tumor necrosis factor-α (TNFα) is involved in tubulointerstitial cell proliferation and apoptosis in obstructive renal injury. Two TNFα receptors (TNFRs), TNFR1 and TNFR2, are known to exist. On TNFα binding, TNFR1 recruits TNFR-associated death domain (TRADD), an asse...

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Main Authors: Misaki, Taro, Yamamoto, Tatsuo, Suzuki, Sayuri, Fukasawa, Hirotaka, Togawa, Akashi, Ohashi, Naro, Suzuki, Hiroyuki, Fujigaki, Yoshihide, Oda, Toshiaki, Uchida, Chiharu, Kitagawa, Kyoko, Hattori, Takayuki, Kitagawa, Masatoshi, Hishida, Akira
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708796/
https://ncbi.nlm.nih.gov/pubmed/19541932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080884
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